What's New?
Great news! The latest enhancements to Thomson Reuters IntegritySM are now available.
One of the most exciting developments is a brand-new content set focused on Experimental Models. Other new developments in Integrity bring new functionality such as new export formats, upgrades in structure editor compatibility, drug-biomarker use links, and links between Integrity and MetaCore™.
NEW KNOWLEDGE AREA: EXPERIMENTAL MODELS
The Experimental Models Knowledge Area details in vivo experimental models that have been used to replicate a disease condition to test the pharmacological activity of drugs. Use this new Knowledge Area to:
- Learn about new models as they emerge
- Understand what models are available for development
- Validate models for internal research
- Understand how many drugs have been tested in these models
- Identify how these drugs performed — were they successful? Did they translate?
- How much supporting documentation is there for this model?
- Identify the models used for the leading drugs and competitors in your field
This initial release of the Experimental Models Knowledge Area covers the Integrity backfile of in vivo models for Cancer and Infections with related data found in the Experimental Pharmacology Knowledge Area. Models for all therapeutic areas as documented in new references emerging in the biomedical and patent literature will be added on an on-going basis, and over the coming months we will complete the backfile of models for all therapeutic areas. Click here to see a roadmap of the planned coverage.
NEW FUNCTIONALITY ENHANCEMENTS
- EXPORT ENHANCEMENTS
Export enhancements include: ISIS to Excel; SMILES in batch; export SAR (structure-activity relationship) Tables from Experimental Pharmacology Knowledge Area; export Experimental Pharmacology data in SDFile format.
- STRUCTURE EDITOR UPGRADES
Upgraded structure editor compatibility for: Accelrys Draw 4; Chime SP8 (for use with ISIS/Draw™ 2.5); CS ChemDraw™ v. 12.
- DRUG-BIOMARKER LINKS
With links from drugs to early-stage biomarker uses, you won’t miss any information. View biomarker development from the earliest stage (i.e., Validity = Experimental) and throughout biomarker development. (For licensed users of the Biomarkers Module of Integrity.)
- INTEGRITY-METACORE LINKS
With new links to MetaCore, you could gain rapid and reliable interworking, saving time and getting to the information required without performing further searches. (License required for access to products.)
Click here for more details on the new developments.
We are constantly looking to make Integrity your indispensible research tool, so if you have any comments or queries on the new features, please do not hesitate to get in touch.
Join our online training session and in 30 minutes Discover the new Experimental Models in Thomson Reuters Integrity:
- Thursday, May 3, 2012
New York 10am – London 3pm – Paris 4pm
Register - Tuesday, May 15, 2012
London 10am – Paris 11am – Mumbai 2:30pm
Register
ONLINE TRAINING
The Getting Started sessions give an overview of Integrity and an introduction to basic search strategies & some key data management tools. Join any of our other training sessions to learn about more specific content or functionalities of Integrity.
GETTING STARTED WITH THOMSON REUTERS INTEGRITY (60 minutes):
- Wednesday, April 11, 2012
London 10am – Paris 11am – Mumbai 2:30pm
Register - Tuesday, April 17, 2012
New York 10am – London 3pm – Paris 4pm
Register - Wednesday, May 23, 2012
New York 10am – London 3pm – Paris 4pm
Register - Thursday, May 10, 2012
London 10am – Paris 11am – Mumbai 2:30pm
Register
HOW TO BEST USE QUICK SEARCH IN THOMSON REUTERS INTEGRITY (30 minutes):
- Tuesday, April 3, 2012
New York 10am – London 3pm – Paris 4pm
Register - Thursday, April 19, 2012
London 10am – Paris 11am – Mumbai 2:30pm
Register
OTHER QUICK GUIDES:
See our library of Quick Guides here.
- Overview
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Thomson Reuters Integrity is a unique knowledge solution integrating biology, chemistry and pharmacology data to empower your discovery and development activities right where you need it most — at the bench.
Improve lead optimization and reduce late stage attrition by:
- Identifying targets of interest that link to related molecular structures
- Creating SAR tables at the click of a button
- Viewing the latest structures, scaffolds and synthetic routes emerging from patents
- Understanding mechanisms of action and disease pathways
- Finding and analyzing numerical PK data to support your biological assays
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The Changing Role of Chemistry in Drug Discovery
Coinciding with the 2011 International Year of Chemistry celebrations, Thomson Reuters has produced a report titled “The Changing Role of Chemistry in Drug Discovery”. The report delivers an action-packed in depth review of the changing role of Chemistry and of Chemists in today's drug discovery research programs. With the input from many key pharmaceutical industry players, supported with data from Thomson Reuters IntegritySM, it examines how life in drug discovery has changed and how it will continue to change and adapt in the future.
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